The available evidence suggests that valerian might improve sleep quality without producing side effects. A dichotomous outcome of sleep quality (improved or not) was reported by 6 studies and showed a statistically significant benefit (relative risk of improved sleep = 1.8, 95% confidence interval, 1.2-2.9), but there was evidence of publication bias in this summary measure. Most studies had significant methodologic problems, and the valerian doses, preparations, and length of treatment varied considerably. An extensive literature search identified 16 eligible studies examining a total of 1093 patients. A systematic review of randomized, placebo-controlled trials of valerian for improving sleep quality is presented. Extracts of the roots of valerian ( Valeriana officinalis) are widely used for inducing sleep and improving sleep quality. Insomnia affects approximately one-third of the adult population and contributes to increased rates of absenteeism, health care use, and social disability.
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